Trades between St. Louis Cardinals & Chicago White Sox
- July 31, 2016- The White Sox traded reliever Zack Duke to the Cardinals in exchange for minor leaguer Charlie Tilson.
- June 29, 2005: The Chicago White Sox purchased Wilton Guerrero from the St. Louis Cardinals.
- February 9, 1999: The Chicago White Sox traded John Ambrose (minors) to the St. Louis Cardinals for Sean Lowe.
- April 3, 1991: The St. Louis Cardinals traded Joe Hall to the Chicago White Sox for Willie Magallanes (minors).
- February 9, 1988: The St. Louis Cardinals traded Ricky Horton, Lance Johnson and cash to the Chicago White Sox for Jose DeLeon.
- July 30, 1987: The Chicago White Sox traded Bryce Hulstrom (minors) to the St. Louis Cardinals for Dave LaPoint.
- December 22, 1986: The Chicago White Sox traded Bill Dawley to the St. Louis Cardinals for Fred Manrique.
- October 23, 1978: The Chicago White Sox traded Jim Willoughby to the St. Louis Cardinals for John Scott.
- December 5, 1977: The Chicago White Sox traded Jim Otten to the St. Louis Cardinals for Stan Butkus (minors).
- August 31, 1977: The St. Louis Cardinals traded Clay Carroll to the Chicago White Sox for players to be named later. The Chicago White Sox sent Nyls Nyman (September 2, 1977), Dave Hamilton (November 28, 1977) and Silvio Martinez (November 28, 1977) to the St. Louis Cardinals to complete the trade.
- August 20, 1977: The Chicago White Sox traded Steve Staniland (minors) to the St. Louis Cardinals for Don Kessinger.
- March 23, 1977: The Chicago White Sox traded Clay Carroll to the St. Louis Cardinals for Lerrin LaGrow.
- December 15, 1976: The St. Louis Cardinals traded Randy Wiles to the Chicago White Sox for Tony La Russa.
- December 12, 1975: The St. Louis Cardinals traded Buddy Bradford and Greg Terlecky to the Chicago White Sox for Lee Richard.
- August 1, 1975: The St. Louis Cardinals purchased Lloyd Allen from the Chicago White Sox.
- June 30, 1975: The St. Louis Cardinals traded a player to be named later and cash to the Chicago White Sox for Buddy Bradford. The St. Louis Cardinals sent Bill Parsons (July 7, 1975) to the Chicago White Sox to complete the trade.
- April 27, 1974: The St. Louis Cardinals traded Ken Tatum to the Chicago White Sox for Luis Alvarado.
- October 26, 1973: The St. Louis Cardinals traded Jim Kremmel to the Chicago White Sox for Denny O’Toole.
- August 29, 1973: The St. Louis Cardinals purchased Eddie Fisher from the Chicago White Sox.
- May 16, 1972: The Chicago White Sox traded Lowell Palmer to the St. Louis Cardinals for Santiago Guzman.
- October 13, 1967: The St. Louis Cardinals purchased Jim Hicks from the Chicago White Sox.
- December 14, 1966: The St. Louis Cardinals traded Don Dennis and Walt Williams to the Chicago White Sox forLeland White (minors) and John Romano.
- November 24, 1964: The St. Louis Cardinals purchased Fritz Ackley from the Chicago White Sox.
- July 7, 1964: The Chicago White Sox purchased Jeoff Long from the St. Louis Cardinals.
- July 24, 1962: The St. Louis Cardinals traded Joe Shipley to the Chicago White Sox for Alan Brice.
- November 27, 1961: The Chicago White Sox traded Minnie Minoso to the St. Louis Cardinals for Joe Cunningham.
- May 19, 1960: The Chicago White Sox purchased Frank Barnes from the St. Louis Cardinals.
- May 25, 1954: The St. Louis Cardinals purchased Bob Boyd from the Chicago White Sox. (Date given is approximate. Exact date is uncertain.)
- June 8, 1953: The St. Louis Cardinals purchased Allie Clark from the Chicago White Sox.
- April 25, 1950: The St. Louis Cardinals purchased Chuck Kress from the Chicago White Sox.
- December 1947: The Chicago White Sox purchased George Genovese from the St. Louis Cardinals.
- September 11, 1932: The St. Louis Cardinals traded Evar Swanson to the Chicago White Sox for players to be named later. The Chicago White Sox sent Jack Rothrock (November 2, 1932) and Carey Selph (November 2, 1932) to the St. Louis Cardinals to complete the trade.
- July 5, 1932: The St. Louis Cardinals traded Joel Hunt and Jake Miller to the Chicago White Sox for Hal Anderson.