Not many trades involving these teams.
- December 14, 2017. The Miami Marlins traded Marcell Ozuna to the St. Louis Cardinals for Daniel Castano (minors), Sandy Alcantara, Zac Gallen, and Magneuris Sierra.
- July 24, 2015. The Miami Marlins traded Steve Cishek to the St. Louis Cardinals for Kyle Barraclough.
- July 31, 2012. The Miami Marlins traded Edward Mujica to the St. Louis Cardinals for Zack Cox (minors).
- April 9, 2001. The St. Louis Cardinals sent John Mabry to the Florida Marlins as part of a conditional deal.
- December 14, 1998. The St. Louis Cardinals traded Armando Almanza, Braden Looper and Pablo Ozuna to the Florida Marlins for Edgar Renteria.